should you take calcium supplements with prolia

Prolia (denosumab) injection, for subcutaneous use. The two most common forms of arthritis are osteoarthritis and rheumatoid arthritis (RA). Prolia contains the active drug denosumab, and Reclast contains the active drug zoledronic acid. But its not clear how often this side effect occurred in clinical trials. If you need to have any dental work (especially surgery), tell the dentist ahead of time that you are using Prolia. These factors include what your insurance plan covers. This may help to protect healthy cells from damage. It works with your immune system to help prevent bone loss. This can cause your weight to change and may explain any weight gain since starting Prolia treatment. Learn more about some of the side effects Prolia may cause. * Sex and gender exist on spectrums. If you have more questions about what to expect with dental procedures while youre taking Prolia, talk with your doctor or dentist. They may help you identify other possible causes or suggest ways to help manage hair loss. Place them in a puncture-proof "sharps" container and dispose of it following state or local laws. Tingling or numbness in the hands, feet, and face can develop as a symptom of severe hypocalcemia. Calcium has active ingredients of calcium. Inflammation of the inner lining of the heart (endocarditis) due to an infection may also happen more often in people who take Prolia. If youd like to learn more about Prolia, talk with your doctor or pharmacist. if you are taking medicine that lower your blood calcium levels. This increases your risk for bone fractures. This is the drugs mechanism of action. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Your doctor or pharmacist can tell you more about the potential side effects of Prolia and ways to reduce them. Doing so will help you avoid the risk for a low calcium level during treatment. or cannot use another osteoporosis medicine or other osteoporosis medicines did not work well. Below are answers to some commonly asked questions about Prolia. You may need to have a dental exam before you begin treatment with Prolia. (BMD is a measurement of the amount of minerals such as calcium in your bones.) Visit your doctor or health care professional for regular checks on your progress. But this isnt the case with Prolia. All subjects in the clinical trials of Prolia received 800mg of calcium and Breastfeeding. Most Medicare plans and other insurance plans cover Prolia. They may want to check for other causes. WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health. Yoga is an excellent way to manage symptoms of osteoporosis. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed. WebIn many individuals, calcium supplements are better absorbed when taken with food. Medically reviewed by Sanjai Sinha, MD. If you have serious side effects from Prolia, call your doctor right away. to treat osteoporosis in males* and in females* whove gone through, to treat osteoporosis caused by long-term use of, metabolic bone disease, such as Hajdu-Cheney syndrome and juvenile. Some people have developed unusual fractures in their thigh bone. And ask your doctor about which drug is right for your condition. (2021). Results may vary. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug class: miscellaneous bone resorption inhibitors. You should always consult your doctor or another healthcare professional before taking any medication. Sciatica was a less common side effect in females* who received Prolia for osteoporosis after menopause. Allergic reaction. These treatments may include acetaminophen (Tylenol) or ibuprofen (Advil, Motrin). Prolia is a prescription medicine used to treat bone loss in men who are at high risk for fracture receiving certain treatments Copyright 1996-2023 Cerner Multum, Inc. You may be more likely to develop osteonecrosis of the jaw if you have cancer or have been treated with chemotherapy, radiation, or steroids. Costs of prescription drugs can vary depending on many factors. For more information, you can refer to the drugs prescribing information. Specifically, Prolia is a monoclonal antibody (a lab-made protein). Its important to discuss all your concerns with your doctor. Call your doctor for medical advice about side effects. Other drugs may interact with denosumab, including prescription and over-the-counter medicines, vitamins, and herbal products. Your doctor should examine your mouth before you start Prolia and may tell you to see your dentist. Your doctor can check if you have osteoporosis, have low BMD, or have osteopenia by measuring your bone density. Your dentist may have you use a chlorhexidine mouth rinse before and after surgery to reduce your risk for jaw-related side effects. So, dont be afraid to ask questions or offer feedback on your treatment. For Xgeva, talk to your pediatrician regarding the use of this medicine in children. Because these reports happened after the studies, it isnt known for sure whether Prolia caused hair loss, or if it was due to another reason. eHealthMe is studying from 146,783 Calcium users for its effectiveness, alternative drugs and more. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Please know that the sponsors of this site are not responsible for content on the site you are about to enter. Youll receive Prolia from a healthcare professional as an injection under the skin in one of the following areas: Prolia contains the active drug denosumab, which is a biologic medication. But its not clear whether this side effect occurred in clinical studies. The risk is real, but rare. These articles might help: Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. Prolia is a medicine that may affect the ability of your body to fight infections. WebStudies have shown that people who live more sedentary lifestyles are at an increased risk of developing osteoporosis. Theyre commonly used to treat osteoporosis. The drug attaches to the RANK protein and helps prevent osteoclasts from breaking down bone. * For more information on this side effect, see the Side effect focus section below. If your pain is more severe, your doctor may suggest prescription pain medication or physical therapy. These are serious. You should take calcium and vitamin D as your doctor tells you to while you receive Prolia. It comes as a liquid solution thats given as an injection. It could harm the unborn baby or cause birth defects. They can tell you more about benefits and risks of Prolia and Forteo. Some reports may have incomplete information. It can have some side effects, but these may depend on who uses it. These medications have different active ingredients and they belong to different groups of drugs. Had parathyroid or thyroid surgery (glands located in your neck), Have been told you have trouble absorbing minerals in your stomach or intestines (malabsorption syndrome), Have kidney problems or are on kidney dialysis, Are taking medicine that can lower your blood calcium levels, Plan to have dental surgery or teeth removed, Are breast-feeding or plan to breast-feed. These side effects include: Your risk for these serious side effects may be higher if youre older and have certain dental procedures. Use of the term male in this article refers to sex assigned at birth. Call your doctor right away if you have an allergic reaction to Prolia. for breast cancer that has not spread to other parts of the body. 2,4. These side effects may include: Its not known what percentage of people in clinical trials developed dental or jaw-related side effects. Last medically reviewed on November 29, 2022. Tell your doctor if youd like to know more about these drugs. Theyll also discuss with you how to lower your risk for fractures by adding other treatments or making certain lifestyle or diet choices. Here are a few questions to consider asking your doctor: You can also learn more about osteoporosis treatment options here. The Prolia is making my leg bones and jaw bones hurt. This medication guide provides information about the Prolia brand of denosumab. may occur. If youre pregnant or breastfeeding, or considering either, talk with your doctor. Research has shown people who take Prolia are at an increased risk of serious infections leading to hospitalizations, including endocarditis and serious infections of the skin, abdominal, urinary tract, and ear. Follow your doctor's instructions. A special MedGuide will be given to you before each treatment. After your treatment with Prolia is stopped, or if you skip or delay taking a dose, your risk for breaking bones, including bones in your spine, is increased. Call your doctor at once if you have a fever, chills, pain or burning when you urinate, severe stomach pain, cough, shortness of breath, skin problems, numbness or tingling, severe or unusual pain, or skin problems. (Biosimilars are like generic drugs. What is the most important information I should know about Prolia? Xgeva is used to treat a high calcium level due to cancer and to prevent bone fractures and other bone problems caused by multiple myeloma or cancer bone metastases. Is the ketogenic diet right for autoimmune conditions? After you have taken Prolia out of the refrigerator, you may keep it at room temperature for up to 14 days. This could include having: Before taking Prolia, share your dental history with your doctor. Some side effects of Prolia may go away on their own within a few days or weeks after starting treatment. The use of the eHealthMe site and its content is at your own risk. They may also suggest exercises to help improve your bone strength and lower your risk for fractures and osteoporosis. While this drug may be prescribed for children as young as 13 years for selected conditions, precautions do apply. Prolia contains the same medicine as XGEVA (denosumab). Prolia was the right choice for me because it worked for me and it was 1 shot every 6 months. We do not endorse non-Cleveland Clinic products or services. Its important to practice good oral hygiene during Prolia treatment. If you cant properly absorb calcium or other minerals, be sure to talk with your doctor before using Prolia. What should I know about Prolia vs. Fosamax? For instance, if you have a health condition that causes excess calcium in We comply with the HONcode standard for trustworthy health information. You may be interested in learning how Prolia compares to the medication Fosamax. Forteo is given as a self-injection once daily. If you plan to drink alcohol while using Prolia, ask your doctor how much is safe to drink. Before your appointment, write down questions, such as: How will Prolia affect my body, mood, or lifestyle? To learn more about this, see the How is Prolia administered? section below. If your Prolia treatment is stopped, talk to your doctor about other medicine that So be sure to tell your doctor about all your health conditions before taking Prolia. You may wonder how Prolia compares to the medication Zometa. Before beginning treatment with Prolia, ask your doctor about the benefits and risks of the drug. These problems may include: Your risk for mouth-related side effects may be higher if you have problems with your teeth. Doing so will help to prevent dental problems. Musculoskeletal pain refers to pain in your bones, muscles, tendons, and ligaments. Serious infections may occur during treatment with Prolia. But before taking Prolia, be sure to tell your doctor about all medications you take (including prescription and over-the-counter types). Theyll also usually treat the hypocalcemia right away. Also, its important to brush and floss your teeth regularly while youre using Prolia. For more information about how Prolia and Zometa compare with each other, see this article. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. You should take calcium and vitamin D as your doctor tells you to while you receive Prolia. Take good care of your teeth and gums while you receive Prolia. Heres a short list of some of the mild side effects that Prolia can cause. Symptoms may include jaw pain or numbness, red or swollen gums, loose teeth, gum infection, or slow healing after dental work. Now i am worried that i've been taking K2 which also takes calcium from the blood to the bones. The most common side effects of Prolia in men with osteoporosis are back pain, joint pain, and common cold (runny nose or sore throat). Over time, Prolia helps to improve the density and strength of your bones by slowing bone loss. Courtney Sullivan, Certified Yoga Instructor, Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT. A severe jawbone problem called osteonecrosis has rarely been reported with Prolia. Dosage of drugs is not considered in the study. It is often used in osteoporosis. Having a tooth extraction while youre using Prolia may increase your risk for these side effects. You do not give Prolia to yourself. All rights reserved. Dizziness from Prolia is usually mild and may go away on its own within a few days or weeks. This includes proper brushing, flossing, mouthwash use, and regular professional dental cleanings. They can also include swelling of your tongue, mouth, or throat, which can cause trouble breathing. Visit www.fda.gov/medwatch, orcall1-800-FDA-1088. Medication Guide. People need calcium for bone health and other functions. If your dizziness doesnt go away or becomes severe, talk with your doctor. If you need to have any dental work (especially surgery), tell the dentist ahead of time that you are receiving this medicine. If they find any cavities or infection, theyll typically delay having you receive Prolia until your dental problems are treated. And they want you to get the best care possible. They can give you more details about this possible side effect and suggest ways to manage it. Learn about the different options, including the benefits of each and any potential side, A FRAX score can help predict the risk of fractures in people with osteoporosis. Keep out of the reach of children and pets. Although its rare, your doctor may give you the option to self-inject Prolia at home. WebTake calcium and vitamin D as directed by your doctor, usually 1000 milligrams of calcium and at least 400 IU of vitamin D daily. Talk with your doctor if youd like to know about taking generic denosumab. The drug may increase the risk of pregnancy loss. The risk is highest in people with cancer, blood cell disorders, pre-existing dental problems, or people treated with steroids, chemotherapy, or radiation. For example, an over-the-counter pain reliever can often ease mild pain such as joint or muscle pain, or headache. Other conditions associated with osteonecrosis of the jaw include blood clotting disorders, anemia (low red blood cells), and a pre-existing dental problem. Peripheral edema is a less common side effect that was reported in clinical studies of females* who received Prolia for osteoporosis after menopause. If you have questions about treatment options for osteopenia or arthritis, talk with your doctor. This aids in keeping your calcium level within the recommended range. By stopping RANKL from binding to its receptor Prolia reduces bone breakdown, bone loss, bone pain, and other bone complications. These side effects may be temporary, lasting a few days or weeks. Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. This list doesnt include all possible mild side effects of the drug. such as inflammation of your skin (dermatitis), rash, and eczema have been reported. Serious side effects that have been reported and their symptoms include: * To learn more, see Does Prolia cause long-term side effects? in the FAQs about the side effects of Prolia section below. But theyre each effective in treating osteoporosis and preventing bone loss. Constipation was also reported as a side effect in females using Prolia for osteoporosis. Call your doctor right away if you have signs of infection such as: swelling, pain, tenderness, warmth, or redness anywhere on your body; pain and burning when you urinate, painful urination; bladder infection (painful or difficult urination); lung infection (cough, shortness of breath); cold symptoms such as stuffy nose, sneezing, sore throat; This is not a complete list of side effects and others may occur. But Prolia is given once every 6 months by a healthcare professional. BMD was increased by 8.8% at the lumbar spine, 6.4% at the total hip, and 5.2% at the femoral neck in trials that measured BMD after three years of treatment with Prolia. With bone loss, your body loses old bone tissue faster than it makes new bone tissue. There are no known interactions with Prolia and other medications, supplements, or other products. Pregnancy. You may take the carton out of the refrigerator and allow it to reach room temperature before the injection is given. Prolia contains the active ingredient denosumab. Prolia works by targeting a molecule called RANKL that osteoclasts need to work. You may have questions about Prolia and your treatment plan. If your pain becomes severe, your doctor may recommend other treatment options to replace Prolia. Can you drink alcohol while taking Prolia? But if the side effects last longer than that, bother you, or become severe, be sure to talk with your doctor or pharmacist.

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