pityriasis rosea after covid vaccine

(2006) 12:1. doi: 10.5070/D380D8301D, 11. Many Americans become infected with them at an early age. JAAD Case Rep. (2018) 4:8001. FOIA -, Welsh E, Cardenas-de la Garza JA, Cuellar-Barboza A, Franco-Marquez R, Arvizu-Rivera RI. 2023 The Authors. New urticaria in the weeks after COVID-19 vaccination (March 2023) OTHER DERMATOLOGY. and transmitted securely. Apply a moisturizer, calamine lotion or a nonprescription . 2023 Apr;11(4):e804. Careers. Spongiotic dermatitis was the most commonly reported cutaneous reaction to COVID-19 vaccination among patients who also had biopsy results available for review, according to a registry-based. and transmitted securely. HHS Vulnerability Disclosure, Help Table 1. Cebeci Kahraman F, Sava Erdoan S, Akta ND, Albayrak H, Trkmen D, Borlu M, Arca DA, Demirba A, Akbayrak A, Polat Ekinci A, Gkek GE, elik HA, Taolar MK, An , Temiz SA, Hazinedar E, Ayhan E, Hzl P, Solak E, Kl A, Ylmaz E. J Cosmet Dermatol. government site. 10.1007/S10354-021-00876-0 Keywords: Reply to "the significance of investigating clinical, histopathologic and virological features in pityriasis rosea and pityriasis rosea-like eruptions following COVID-19 vaccinations" by Ciccarese G. et al. Khan I, Elsanousi AA, Shareef AM, Tebha SS, Arif A, Gul S. Immun Inflamm Dis. Abdullah L, Hasbani D, Kurban M, Abbas O. Int J Dermatol. 2021 Dec;108(6):317-318. doi: 10.12788/cutis.0411. Pityriasis rosea is a common viral infection that usually affects individuals between 10-35 years of age. All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. HHS Vulnerability Disclosure, Help Please enable it to take advantage of the complete set of features! Other plausible theories include molecular mimicry with viral epitopes and type IV delayed hypersensitivity reaction (12). 2020;96(1142):753758. HHS Vulnerability Disclosure, Help As previously mentioned, only some cases of PR/PRLE after anti-SARS-CoV-2 vaccination have been reported (Table 2).1-18, PRLE usually appears following a drug, without prodromal symptoms. Human herpesviruses 6 and 7 are common. This is called a herald patch and may be up to 4 inches (10 centimeters) across. Epub 2021 Aug 26. Factors affecting the severity of central centrifugal cicatricial alopecia. HHS Vulnerability Disclosure, Help Cutis. Unfortunately, due to her deteriorating neurologic status, her associated symptoms were not evaluated properly. As a library, NLM provides access to scientific literature. 2021 Sep 7;8:752443. doi: 10.3389/fmed.2021.752443. An official website of the United States government. Epub 2022 Jan 5. Coronavirus pandemic (COVID-19), McMahon D.E., Amerson E., Rosenbach M., et al. Pityriasis rosea is a rash that often begins as an oval spot on the face, chest, abdomen or back. Dermatol Reports. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Although the exact pathophysiologic mechanisms of PR after vaccination remain unclear, immune responses to COVID-19 vaccines and disruption of T-cell mediated control of latent infections were implicated (12, 1518). PR has also been reported to follow COVID-19 vaccination (11). Federal government websites often end in .gov or .mil. Unauthorized use of these marks is strictly prohibited. 1. Immunity, Inflammation and Disease published by John Wiley & Sons Ltd. Accessibility 2022 Jul 21;14(7):e27108. While COVID-19 vaccines offer strong and lasting protection against severe . Before The most commonly inoculated vaccines include those against smallpox, followed by tuberculosis, poliomyelitis, influenza, and human papillomavirus virus (12, 13). Pityriasis rosea after mRNA COVID-19 vaccination Pityriasis rosea after mRNA COVID-19 vaccination Pityriasis rosea after mRNA COVID-19 vaccination Pityriasis rosea after mRNA COVID-19 vaccination Int J Dermatol. Pityriasis Rosea Induced by COVID-19 Vaccination Eur J Case Rep Intern Med. These types cannot cause cold sores or genital herpes. Before Pityriasis Rosea Associated With COVID-19 Vaccination: A Common Rash Following Administration of a Novel Vaccine. CONCLUSION: The association between pityriasis rosea and pityriasis rosea-like eruptions after Covid-19 vaccines was established, but given the scarcity of studies, there is a need to conduct different clinical trials to confirm this association further and study the etiology and mechanism of the disease. N Engl J Med 2020; 383: 2603-2615. Dermatol Ther. eCollection 2022 Jul. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher. Data were independently extracted and accessed for bias. Unauthorized use of these marks is strictly prohibited. Pityriasis rosea-like eruption after Pfizer-BioNTech COVID-19 vaccination Pityriasis rosea-like eruption after Pfizer-BioNTech COVID-19 vaccination Pityriasis rosea-like eruption after Pfizer-BioNTech COVID-19 vaccination Pityriasis rosea-like eruption after Pfizer-BioNTech COVID-19 vaccination Br J Dermatol. -, Carballido Vzquez AM, Morgado B. Pityriasis rosea-like eruption after PfizerBioNTech COVID-19 vaccination. Vaccine-induced pityriasis rosea and pityriasis rosea-like eruptions: a review of the literature. *Correspondence: Poonkiat Suchonwanit, poonkiat@hotmail.com, ORCID: Kanchana Leerunyakul orcid.org/0000-0002-0669-5611Kallapan Pakornphadungsit orcid.org/0000-0003-4783-0282Poonkiat Suchonwanit orcid.org/0000-0001-9723-0563, COVID-19 Associated Cutaneous Manifestations and COVID-19 Vaccine Related Skin Reactions, View all Figure 2. Skin lesions appeared in a 49-year-old female 8 days after the first dose of the BNT162b2 mRNA vaccine and in a 53-year-old male 7 days after the second dose of the same vaccine. Drago F, Ciccarese G, Rebora A, Parodi A. Pityriasis rosea is generally benign and most of the time will not come back after a patient has recovered, but in a small number of cases the condition recurs which may be a sign, there is another underlying condition causing the rash.. In the period May 2021- February 2022 we observed five cases of clinically typical PR that appeared 2 to 3 weeks after anti-SARS-CoV-2 vaccination with BNT162b2 (3 patients) or mRNA- 1273 (2 patients). 2 min read January 12, 2022 - 6:26AM A Sydney-based woman has credited her booster dose of the Covid-19 vaccine with removing two persistent warts she's had for five years. Cutaneous reactions after COVID-19 vaccination in Turkey: A multicenter study. doi: 10.1111/dth.15129. Nicotinamide does not prevent skin cancer in solid organ transplant recipients (March 2023) URTICARIA AND ANGIOEDEMA. Pityriasis Rosea Shortly After mRNA-1273 COVID-19 Vaccination. It is believed to represent a delayed reaction to viral infections and is usually associated with endogenous systemic reactivation of human herpesvirus (HHV) 6 and / or 7 (1). Cutaneous reactions reported after Moderna and Pfizer COVID-19 vaccination: A registry-based study of 414 cases. Before Keywords: Clipboard, Search History, and several other advanced features are temporarily unavailable. Authors Elina Khattab 1 , Eirini Christaki 2 , Constantinos Pitsios 1 Affiliations 1 Medical School, University of Cyprus, Nicosia, Cyprus. Peripheral eosinophilia is often present. Veraldi S, Boneschi V, Cusini M, Maronese CA. An official website of the United States government. Pityriasis rosea (PR)-like eruption is a cutaneous complication associated with several medications and vaccinations. Alvin Friedman-Kien, MD, walked through the doorway into the exam room, looked at me and immediately said, "Oh, you have pityriasis rosea." He called in a bunch of residents so he could show them my rash and teach them about the condition, which often has a large patch called the "mother patch" (or herald patch), as well as smaller . An official website of the United States government. doi: 10.1111/ijd.13061. 2021;184(6):11941195. Before McMahon DE, Amerson E, Rosenbach M, Lipoff JB, Moustafa D, Tyagi A, Desai SR, French LE, Lim HW, Thiers BH, Hruza GJ, Blumenthal KG, Fox LP, Freeman EE. Disclaimer. Only a few cases of pityriasis rosea (PR)/pityriasis rosea-like eruption (PRLE) after anti-SARS-CoV-2 vaccination have been reported. MeSH Abstract Dear Editor, Pityriasis rosea (PR) is a common, self-limited erythematous papulosquamous dermatosis that mainly affects young adults. tivation is associated with pityriasis rosea-like eruption.6 Our cases of herpes simplex and pityriasis rosea-like eruption occurred in male patients following the first dose of BioNTech, whereas one female patient suffered herpes zoster following the third dose of CoronaVac. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Reactions related to the hair have so far not been reported. Inclusion in an NLM database does not imply endorsement of, or agreement with, Dermatol Ther. Cyrenne BM, Al-Mohammedi F, DeKoven JG, Alhusayen R. Pityriasis rosea-like eruptions following vaccination with BNT162b2 mRNA COVID-19 vaccine, Cutaneous adverse reactions after m- RNA COVID-19 vaccine: early reports from Northeast Italy. (2017) 9:7399. doi: 10.4081/dr.2017.7399, 17. Please enable it to take advantage of the complete set of features! walker hayes daughter. Some patients may have a cold before the rash. reactions included pernio/chilblains, cosmetic ller reactions, zoster, herpes simplex ares, and pityriasis rosea-like reactions. Origin, transmission, diagnosis and management of coronavirus disease 2019 (COVID19). We report 10 . Cutaneous Reactions Following COVID-19 Vaccination: A Review of the Current Literature. Federal government websites often end in .gov or .mil. FOIA 2022 Jul 6;15(1):9503. doi: 10.4081/dr.2022.9503. Pityriasis rosea after mRNA COVID-19 vaccination. The significance of investigating clinical, histopathologic and virological features in pityriasis rosea and pityriasis rosea-like eruptions following COVID-19 vaccinations. Moreover, while dermoscopy may facilitate the diagnosis of PR, its utility for atypical PR or PR-like lesions is still limited. Postgrad Med J. sharing sensitive information, make sure youre on a federal COVID-19 vaccine hesitancy is a critical problem that hinders It is possible that a relationship between anti- Sars-CoV-2 vaccination and PR/PRLE exists; however, it is very rare, in consideration of millions of vaccinated subjects and the low number of reported cases of PR/PRLE. Careers. Among patients who received inactivated vaccines, another case of PR-like eruption was reported four days after the first dose of CoronaVac (SinoVac) (1). Globally, as of 7:26 pm CEST, 10 October 2022, there have been 618,521,620 confirmed cases of COVID-19, including 6,534,725 deaths, reported to the WHO. (2021) 60:11501. Laboratory investigation results (i.e., complete blood count, blood chemistry, C-reactive protein level, erythrocyte sedimentation rate, serological test for syphilis, plasma polymerase chain reaction (PCR) for human herpesvirus (HHV)-6 and HHV-7, and reverse transcription-PCR for COVID-19) were unremarkable. Vaccinations have been identified to rarely cause several cutaneous reactions. MeSH Figure 3. As our patient did not receive a COVID-19 vaccine, we cannot evaluate the latter based on the present case. KL drafted the original manuscript. PRISMA, preferred reporting. . pityriasis rosea after covid vaccine Last month at Barret-jackson in Scottsdale, Arizona a 1929 Roadster was put up for sale by Dave Kindig of . All patients were treated with cetirizine (20 mg/day for 7-14 days). Pityriasis rosea (PR), PR-like eruptions (PR-LE), and herpes zoster have been frequently reported during the COVID-19 pandemic and following COVID-19 vaccination. Authors Lina Abdullah 1 government site. Results were superimposable: parakeratosis, mild spongiosis, acanthosis and exocytosis were seen in the epidermis. Epub 2022 Jan 31. The .gov means its official. FOIA Pityriasis rosea is a common self-limiting rash that usually starts with a herald patch on the trunk and progresses along the Langer lines to a generalized rash over the trunk and limbs. and transmitted securely. Pityriasis Rosea Associated With COVID-19 Vaccination: A Common Rash Following Administration of a Novel Vaccine. The following self-care tips may help relieve the discomfort of pityriasis rosea: Take nonprescription allergy medicine (antihistamines), such as diphenhydramine (Benadryl, others). Clipboard, Search History, and several other advanced features are temporarily unavailable. Patient n. 1. Although the most severe manifestations concern the lower respiratory tract, COVID-19 is a multiorgan disease that also affects the skin. The authors of one 2014 case report of a 71-year-old man who suffered from pityriasis rosea one month after receiving an influenza vaccine concluded that "altered immunity" could result in. A 52-year-old Thai woman with a one-year history of recurrent glioblastoma was admitted to our hospital for a planned targeted therapy. See this image and copyright information in PMC. and transmitted securely. 2022 Aug;35(8):e15601. Bookshelf Keywords: It is possible that a relationship anti- Sars-CoV-2 vaccinationPR/PRLE exists; however, it is very rare, in consideration of millions of vaccinated subjects and the low number of reported cases with PR/PRLE. Following the national COVID-19 vaccination guidelines, she received a shot of ChAdOx1 nCoV-19 (AZD1222) vaccine before the therapy. Additionally, differences in incidence of this reaction after Pfizer and Moderna vaccination may suggest a differing host immune response incited by these vaccines which warrants further investigation. (2015) 2015:253154. doi: 10.1155/2015/253154, 14. In all patients laboratory examinations were within normal ranges. Accessibility The site is secure. 2022 Jul 6;15(1):9503. doi: 10.4081/dr.2022.9503. Unauthorized use of these marks is strictly prohibited. We observed Figure 1. Br J Dermatol. J Med Virol. Int J Dermatol. Vaccination is one of the cornerstones in the efforts towards ending the coronavirus disease 2019 (COVID-19) pandemic. -, Broccolo F., Drago F., Careddu A.M., et al. doi: 10.1002/iid3.804. We include a review on all cases of PR/PRLE after anti- SARS-CoV-2 vaccination reported in the literature and discuss some pathogenetic hypotheses. Drago F, Broccolo F, Ciccarese G. Pityriasis rosea, pityriasis rosea-like eruptions, and herpes zoster in the setting of COVID-19 and COVID-19 vaccination. See this image and copyright information in PMC. -, Cyrenne BM, Al-Mohammedi F, DeKoven JG, Alhusayen R. Pityriasis rosea-like eruptions following vaccination with BNT162b2 mRNA COVID-19 vaccine. Drago F, Ciccarese G, Parodi A. Pityriasis rosea and pityriasis rosea-like eruptions: How to distinguish them? J Formos Med Assoc. Fortunately, PR-like eruption is responsive to topical corticosteroids without any systemic adverse effects. 2022 Jul 6;15(1):9503. doi: 10.4081/dr.2022.9503. Drago F, Ciccarese G, Javor S, et al. This site needs JavaScript to work properly. (A) Dermoscopic features: dotted and linear vessels forming a network on a yellowish background with some whitish peripheral scales (original magnification x20). Cyrenne BM, Al-Mohammedi F, DeKoven JG, Alhusayen R. J Eur Acad Dermatol Venereol. Results: Cutaneous Sarcoidosis-like Eruption Following Second Dose of Moderna mRNA-1273 Vaccine: Case or Relationship? Bethesda, MD 20894, Web Policies In a registry-based study, PR-like eruption was observed in only 12% of patients (14). We present a case of a pityriasis rosea-like rash occurring after Pfizer COVID-19 vaccination and review cases of pityriasis rosea (PR)/PR-like eruption (PR-LE) after mRNA COVID-19 vaccine published in the medical literature. sharing sensitive information, make sure youre on a federal eCollection 2023 Mar 7. SARS-CoV-2 vaccine; cutaneous side-effects; infection; papulosquamous; skin diseases; vaccine hesitancy. Thirty-one studies were included for data extraction after screening following the eligibility criteria. The site is secure. Cureus. 2021 Dec;108(6):317-318. doi: 10.12788/cutis.0411. This site needs JavaScript to work properly. To the best of our knowledge, there have been no reports of PR-like eruptions following inoculation with Oxford/AstraZeneca ChAdOx1 nCoV-19 (AZD1222) vaccine. official website and that any information you provide is encrypted In 4 patients PR appeared after the first vaccination; in one patient after the second one. J Formos Med Assoc. The face may be involved; involvement of the oral cavity occurs in 50% of patients. He described the appearance of an erythematous centrally scaled lesion at the right part of his abdomen, followed by the spreading of red oval mildly scaling lesions on the trunk, neck, and proximal parts of the upper extremities, which showed in the physical examination (Figure 1, a and b). doi: 10.1111/dth.15601. The https:// ensures that you are connecting to the (2021) 35:e4913. Careers. Complete remission was observed within 14-30 days. Would you like email updates of new search results? eCollection 2022. 2021 Sep;35(9):e546-e548. Martora F, Battista T, Marasca C, Genco L, Fabbrocini G, Potestio L. Clin Cosmet Investig Dermatol. Pityriasis rosea is a common rash that usually begins as a round or oval-shaped patch and spreads in stages in a characteristic pattern. Atzori L, Pinna AL, Ferreli C, Aste N. Pityriasis rosea-like adverse reaction: review of the literature and experience of an Italian drug-surveillance center. Despite this rare complication, our report highlights that the presence of PR-like eruption is not a contraindication for subsequent vaccinations. PR 12.7 days (mean) after the vaccination (19 patients after the 1. Abdullah L, Hasbani D, Kurban M, Abbas O. Pityriasis rosea after mRNA COVID-19 vaccination, Two cases of pityriasis rosea after the injection of coronavirus disease 2019 vaccine, Erythema nodosum, zoster duplex and pityriasis rosea as possible cutaneous adverse effects of Oxford-AstraZeneca COVID-19 vaccine: report of three cases from India, Atypical pityriasis rosea associated with mRNA COVID- 19 vaccine, Post Covid-19 vaccination papulovesicular pityriasis rosea-like eruption in a young male, Pityriasis rosea-like cutaneous eruption as a possible dermatological manifestation after Oxford-AstraZeneca vaccine: case report and brief literature review. HHS Vulnerability Disclosure, Help Potassium hydroxide, syphilis, and laboratory tests were within normal limits. Pityriasis rosea and pityriasis rosea-like eruption after anti-SARS-CoV-2 vaccination: a report of five cases and review of the literature. N Engl J Med 2020; 383:260315. We present two cases of COVID-19 vaccine-induced pityriasis rosea. 2005;124(6):12341240. Suchonwanit P, Triamchaisri S, Wittayakornrerk S, Rattanakaemakorn P. Leprosy Reaction in Thai Population: A 20-Year Retrospective Study. Sriphojanart T, Khunkhet S, Suchonwanit P. A retrospective comparative study of the efficacy and safety of two regimens of diphenylcyclopropenone in the treatment of recalcitrant alopecia areata. The site is secure. sharing sensitive information, make sure youre on a federal Epub 2021 Jul 21. Few brownish patches also appeared, suggestive of post-inflammatory hyperpigmentation. Of the 30 cases found, none experienced severe adverse effects and the rash resolved in an average of 5.6 weeks. Most people with psoriasis should follow the same CDC guidelines for booster shots as the general public, says the NPF. The advent of vaccines has drastically reduced the incidence, morbidity, and mortality related to COVID-19 [1]. Clipboard, Search History, and several other advanced features are temporarily unavailable. -, Johansen M, Chisolm SS, Aspey LD, Brahmbhatt M. Pityriasis rosea in otherwise asymptomatic confirmed COVID-19-positive patients: a report of 2 cases. government site. All authors have made substantial contribution to the work and have approved the final version of this article. Available doctors, insurances and verified patient reviews for Optimized Health and Wellness. Epub 2021 May 29. Safety and efficacy of the BNT162b2 mRNA Covid-19 vaccine. The authors declare no conflict of interest. Disclaimer. The https:// ensures that you are connecting to the Numerous scattered erythematous plaques with fine scale oriented along skin cleavage lines, most appreciable on the upper portion of the chest. 2023 Apr;11(4):e804. 2022 Jun;7:164-168. doi: 10.1016/j.jdin.2022.01.009. J Eur Acad Dermatol Venereol. 21% of people who have Covid develop a rash as their only symptom of infection. PRISMA, preferred reporting items for systematic reviews and metaanalysis. Br J Dermatol. doi: 10.1016/j.jdcr.2018.04.002, 12. Pityriasis rosea and pityriasis rosea-like eruptions: how to distinguish them? J Eur Acad Dermatol Venereol. official website and that any information you provide is encrypted 2021 Dec;108(6):317-318. doi: 10.12788/cutis.0411. eCollection 2022. Perivascular lymphocytic infiltrates with some extravasated erythrocytes were observed in the superficial dermis (Figure 2). 2022 by the American Academy of Dermatology, Inc. Drago F, Ciccarese G, Rebora A, et al. It was found popularly in the trunk area, either asymptomatically or with mild symptoms. [Epub ahead of print]. 2021 Sep;60(9):1150-1151.doi: 10.1111/ijd.15700. The mechanisms behind these COVID-19-related symptoms remain unclear. Cutaneous reactions reported after Moderna and Pfizer COVID-19 vaccination: a registry-based study of 414 cases. MeSH National Library of Medicine Umakanthan S, Sahu P, Ranade AV, et al. sharing sensitive information, make sure youre on a federal eCollection 2023 Mar 7. Epub 2021 May 29. Dermatol Ther. Polack FP, Thomas SJ, Kitchin N, et al. Pityriasis Rosea Following Pfizer-BioNTech Vaccination in an Adolescent Girl. Federal government websites often end in .gov or .mil. Tina Burke, 40, a nurse who works on the oncology floor at Massachusetts General Hospital (MGH), received her first coronavirus shot on Jan. 3. doi: 10.1111/dth.15040, 3. Epub 2022 Mar 8. NCI CPTC Antibody Characterization Program. The latter is found in a younger age group. and transmitted securely. The disease begins with a single erythematous plaque, the so-called herald patch that usually appears on the trunk: it is roundish, pink to red in color and remains the only clinical manifestation for some days, when widespread, clinically similar, although smaller lesions appear. (2016) 30:5445. Morphologic misclassication is possible. Dear Editor, Pityriasis rosea (PR) is a common, self-limited erythematous papulosquamous dermatosis that mainly affects young adults. Cite this: Skin Reactions After COVID-19 Vaccination . 7 Articles, This article is part of the Research Topic, Creative Commons Attribution License (CC BY), Division of Dermatology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand. 2021;35(8):e489e491. NCI CPTC Antibody Characterization Program, Ritchie H., Mathieu E., Rodes-Guirao L., et al. 2022 May;121(5):1003-1007. doi: 10.1016/j.jfma.2021.12.028. Epub 2022 Oct 17. government site. Busto-Leis JM, Servera-Negre G, Mayor-Ibarguren A, et al.. Pityriasis rosea, COVID-19 and vaccination: new keys to understand an old acquaintance, Pityriasis rosea following CoronaVac COVID-19 vaccination: a case report, Pityriasis rosea after administration of Pfizer-BioNTech COVID-19 vaccine. doi: 10.1111/dth.13650, 7. Pityriasis rosea, COVID-19 and vaccination: new keys to understand an old acquaintance. KL and KP collated resources. doi: 10.1111/jdv.17342. However, the etiopathogenetic mechanisms remain largely unknown and further studies are needed in order to clarify the correlation between SARS-CoV-2 and PR. Received 2022 Mar 26; Accepted 2022 Apr 25. The .gov means its official. Pityriasis rosea, pityriasis rosea-like eruptions, and herpes zoster in the setting of COVID-19 and COVID-19 vaccination. government site. However, in cases of atypical PR, it may present with erythema multiforme-like lesions and purpura (5). A spectrum of cutaneous reactions to SARs-CoV-2 (COVID-19) vaccines have been reported in the literature. doi: 10.1111/bjd.20143. Wien Med Wochenschr. PRISMA flowchart. In a Spanish study,PR/PRLE was observed in 11 patients (6.7%) vaccinated with BNT162b2, in 5 patients (3.4%) vaccinated with mRNA- 1273 and in 4 patients (4.2%) vaccinated with AZD1222.2 Available data suggest that BNT162b2 vaccine is more related to PR/PRLE than other vaccines. See this image and copyright information in PMC. SARS-CoV-2 spike protein positivity in pityriasis rosea-like and urticaria-like rashes of COVID-19. It has been reported that pityriasis rosea has been triggered by several vaccines, as a rare side-effect. Four patients were subjected to the second vaccination, but no skin lesions appeared. Please enable it to take advantage of the complete set of features! 2023 Apr;11(4):e804. Would you like email updates of new search results? However, there are limited data on the negative effects of immunological reactivation following vaccination. . (2017) 5:20311. Bethesda, MD 20894, Web Policies Written informed consent was obtained from the individual(s) for the publication of any potentially identifiable images or data included in this article. Accessibility Epub 2022 Feb 9. 8600 Rockville Pike Received: 03 August 2021; Accepted: 17 August 2021; Published: 07 September 2021. The https:// ensures that you are connecting to the Marcantonio-Santa Cruz OY, Vidal-Navarro A, Pesqu D, Gimnez-Arnau AM, Pujol RM, Martin-Ezquerra G. J Eur Acad Dermatol Venereol. This site needs JavaScript to work properly. (2021) 35:e5468. Due to the temporal relationship between vaccination and onset of rash, COVID-19 vaccination was the most likely etiology. The https:// ensures that you are connecting to the Variable dermatological manifestations including acral erythema, urticaria, vasculitis, vesicular or pustular eruptions, maculopapular rash have all been reported during the course of COVID19. The appearance of pityriasis rosea following the first injection of the AstraZeneca vector vaccine suggests a causal connection. Four patients were subjected to the second vaccination, but no skin lesions appeared. MeSH -. PRISMA, preferred reporting items for systematic reviews and metaanalysis. 17% get a rash first and then get other symptoms later on as disease progresses. eCollection 2023 Mar 7. J Eur Acad Dermatol Venereol. McMahon DE, Kovarik CL, Damsky W, et al.. Clinical and pathologic correlation of cutaneous COVID-19 vaccine reactions including V-REPP: a registry-based study. doi: 10.12998/wjcc.v5.i6.203, 6. Would you like email updates of new search results? Qaderi K, Golezar MH, Mardani A, Mallah MA, Moradi B, Kavoussi H, Shamsabadi A, Golezar S. Dermatol Ther. (2020) 33:e13650. This site needs JavaScript to work properly. Temiz SA, Abdelmaksoud A, Dursun R, Durmaz K, Sadoughifar R, Hasan A. J Cosmet Dermatol. After introducing Covid-19 vaccines, a few side effects were reported, pityriasis rosea being one of them. The https:// ensures that you are connecting to the She was prescribed outpatient COVID-19 treatment of azithromycin, vitamins D and C, and then quarantined for 2 weeks. Some studies have identified severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike proteins on endothelial cells and lymphocytes from PR-like lesions, consistent with direct viral invasion (3, 4). Clin Dermatol. Meantime the onset, was 8.58 days, and meantime it took to recover, was 6.44 weeks. Drago F, Ciccarese G, Javor S, Parodi A. Vaccine-induced pityriasis rosea and pityriasis rosea-like eruptions: a review of the literature.

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